Rita Tjokropranoto
University Christian Maranatha, Bandung, Indonesia
Title: Comparison The Anthelminthic Effectvity of Gandarusa Leaves (Justicia gendarussa Burm. F.), Pomegranate Skin (Punica granatum L) Infusion And Papaya Leaves Infusion (Carica papaya L.) Towards Ascaris suum Female In Vitro
Biography
Biography: Rita Tjokropranoto
Abstract
Geohelmiths are mainly a health problem in developing counties. Soil Transmitted Helminth well known of such are Ascaris lumbricoides, Trichuris trichiura, Hookworm. The soil-transmitted helminths (STH) are the world’s most important causes of physical and intellectual growth retardation Ascaris lumbricoides infection is one of the most common intestinal worm infections. High prevalence ascariasis in Indonesia in rural areas with poor sanitation about 80%. Anthelminthic Resistance is a common problem in STH. Most available alternative therapy is derived from plants. The purpose of this study was to analyse the anthelmintic effect and potency of Gandarusa LeavesI Infusion (GLI), Pomegranate Skin Infuson (PSI) and Papaya Leaves infusion (PLI) againts Ascaris suum Female In Vitro. Methodology was a Real laboratory exprimental research design using 960 female worms of Ascaris suum which were divided into 8 groups. The anthelmintic effect tested in vitro. The data measured is the number of death worms after incubated for 3 hours at a temperature of 370C. The data of death worm were analyzed using one-way ANOVA with α = 0.05, if there are differences continued by Tukey HSD test (p = 0.05). Results The GLI, PLI and PSI were differed significantly when compared with negative control with p=0.000 and the Tukey HSD results showed GLI2, GLi3, PSI 2 were not significant when compared with positive control with the value of p >0.05). Conclusion All of GLI, PSI and PLI were have anthelmintic efectivity against Ascaris suum female in vitro and GLI2, GLi3, PSi2 were equivalent with positive control.